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Plant-Mediated Biosynthesis of Nanoparticles Using Cannabis Sativa Extract: A Review

Priyanka Jojo

University Department of Chemistry, Ranchi University, Ranchi, Jharkhand, India

Smriti Singh

University Department of Chemistry, Ranchi University, Ranchi, Jharkhand, India

Anil Kumar Pandey

Department of Chemistry, Jagannath Nagar College, Ranchi, Jharkhand, India

183-193

Vol: 16, Issue: 2, 2026

Receiving Date: 2026-03-10 Acceptance Date:

2026-04-19

Publication Date:

2026-05-09

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http://doi.org/10.37648/ijrst.v16i02.007

Abstract

Biosynthetic approaches for nanoparticle production have garnered considerable attention amid growing interest in green and sustainable chemistry. Plant-derived materials have been used as an alternative method for synthesizing metal and metal oxide nanoparticles, as these approaches are eco-friendly, cost-effective, and energy-efficient, and they eliminate the need for toxic chemicals. Plant extracts have attracted the most interest among bio-entities because of their unique natural properties, which enable them to reduce and stabilize metal nanoparticles in a single-step synthesis. Cannabis sativa has emerged as a highly promising source of green nanoparticles, owing to its unique and diverse phytochemical profile, warranting thorough exploration of its benefits and mechanisms. In this review, we focus on the synthesis of certain metal and metal oxide nanoparticles (M/MO NPs) by using Cannabis sativa plant extract. It is a natural source that may serve as a stabilizing, capping, and reducing agent as it contains various bioactive phytochemicals. Cannabinoids and non-cannabinoid components are among the complex variety of secondary metabolites found in it, including non-cannabinoid phenols, flavonoids, terpenes, alkaloids, and other substances. These constituents result in smaller particles and significantly affect the activities of M/MO NPs.

Keywords: Nanotechnology; Cannabis sativa; Phytochemicals; Green synthesis; Nanoparticles.

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