Design, Synthesis, Characterization and Biological Evaluation of Cu(II), Pd(II) Complexes with Novel Schiff Base Ligand Derived from 3-Amino Coumarin

Kotte Shylaja

Department of Chemistry St. Peter’s Engineering College, Hyderabad.

Padmavathi Papolu

VNR Vignana Jyothi Institute of Engineering and Technology, Hyderabad

Chakilam Vinutha

Department of Chemistry Kakatiya university Warangal.


Vol: 13, Issue: 4, 2023

Receiving Date: 2023-08-30 Acceptance Date:


Publication Date:


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Coumarins(-oxo-2H-chromene) belong to the family of lactones containing benzopyrone skeletal framework that are isolated from plant as well as total synthesis in the laboratory .Furthermore, the pharmacological and biochemical properties as well as therapeutic applications of coumarins depend up on the pattern of substitution. In view of this coumarins have attracted intense interest in recent years because of their pharmacological properties, Hence coumarins havebeenreportedtoposses,amongothers,anticonvulsunts,antiinflammatory,antioxidents,analgesic,anticoagulents,antitumaral,antiviral activities. The novel Schiff base ligand(FYMAC) synthesized by the condensation of furfuraldehyde and 3-aminocoumarin.The nature bonding and geometry of the tranion metal complexes as well as ligand have been deduced from elemental analysis, mass, NMR, IR, ESR& thermal analysis. The complexes are found to have ML4based on elemental, conductance and spectral studies octahedral(cu), square planar (Pd) geometry was assigned for these complexes. The ligand as tetradentate and co-ordinate through N-atom of azo methine group, O-atom of keto group of 3- aminocoumarin.

Keywords: Schiffbase; 3-aminocoumarin; Metal complexes


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