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ANALYSIS OF EFFECT OF CALCIUM, PHOSPHOROUS &ALKALINE PHOSPHATASE ON DENTAL CARIES IN PATIENTS OF DIABETES

Mulla Javed Bakas

Research Scholar, Dept. of Medical Biochemistry, CMJ University, Meghalaya

18-25

Vol: 5, Issue: 2, 2015

Receiving Date: 2015-02-10 Acceptance Date:

2015-03-11

Publication Date:

2015-04-12

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Abstract

Analysis of this study was carried out to role of calcium, phosphorous and alkaline phosphatase in dental caries on the patients of diabetes. Total of 200 subjects of either sex, aged >30 yrs were selected. Decayed, missed replique montre and filled teeth were used as indices for scoring the dental caries and were distributed into 4 groups as 30-40 (Group-I) 41-50 (Group II), 51-60 (Group III) and more than 60 (Group IV), while the control subjects had dmft index equal to or less than 3. Serum was collected and Calcium, phosphate, fluoride and alkaline phosphatase were analyzed. Patients of dental caries showed significantly decreased levels of calcium, phosphate, fluoride (P<0.001) and significantly increased level of alkaline phosphatase (P<0.001) were observed in groups I, II, III and IV as compared to controls. i.e. the diabetic patients are more prone to develop dental caries with calcium, phosphorus levels decreases and alkaline phosphatase level increases. but in diabetic females with dental caries serum phosphorus levels are very low in comparison to diabetic male. The mean dmft index value for the PKU children (4.18) was found to be relatively high as high as compared to the other two groups. No statistically significant difference was found in the mean DMFS values between the children and adolescents in the three groups. Children with PKU possess a higher caries rate in their primary dentition, they show a higher risk of developing periodontal disease.

Keywords: Dental caries, Serum calcium ,Phosphorous, Alkaline phosphatase

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