Many acridines, such as proflavine, also have antiseptic properties. Acridine and related derivatives bind to DNA and RNA due to their abilities to intercalate. Acridine was first isolated in 1871 by Carl Gräbe and Heinrich Caro. Many synthetic processes are known for the production of acridine and its derivatives. Acridine occurs naturally in coal tar. It is separated from coal tar by extracting with dilutesulfuric acid.
Keywords: Acridine derivatives, Dyes, DNA, RNA, Acridophosphine, chrysaniline, chrysaniline and Oxidation.
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