Mendelian inheritance is a set of primary tenets relating to the transmission of hereditary characteristics from parent organisms to their children; it underlies much of genetics. They were initially derived from the work of Gregor Mendel published in 1865 and 1866 which was "re-discovered" in 1900 and were initially very controversial. When they were integrated with the chromosome theory of inheritance by Thomas Hunt Morgan in 1915, they became the core of classical genetics

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References

1. Walker FO (2007). 'Huntington's disease'. Lancet 369 (9557): 218.doi:10.1016/S0140- 6736(07)60111-1. PMID 17240289.
2. Brown (2002), Section 2, Chapter 6: 6.2. Assembly of a Contiguous DNASequence
3. Lodish et al. (2000), Chapter 7: 7.1. DNA Cloning with Plasmid Vectors
4. Davey Smith, G; Ebrahim (2003). ''Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?'. International journal of epidemiology 32 (1): 1–22. doi:10.1093/ije/dyg070. PMID 12689998.
5. Wolf, YI; Rogozin; Grishin; Koonin (2002). 'Genome trees and the tree of life.'. Trends in genetics: TIG 18 (9): 472–9. doi:10.1016/S0168-9525(02)02744-0.PMID 12175808.
6. Gavrilets, S (2003). 'Perspective: models of speciation: what have we learned in 40 years?'. Evolution; international journal of organic evolution 57 (10): 2197– 215. doi:10.1554/02-727. PMID 14628909.
7. Myers RH (2004). 'Huntington's disease genetics'. NeuroRx 1 (2): 255–62. doi:10.1602/neurorx.1.2.255. PMID 15717026.
8. Subramaniam S, Sixt KM, Barrow R, Snyder SH (2009). 'Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity'. Science 324 (5932): 1327–30. doi:10.1126/science.1172871. PMID 19498170.
9. Cattaneo E, Zuccato C, Tartari M (2005). 'Normal huntingtin function: an alternative approach to Huntington's disease'. Nat. Rev. Neurosci. 6 (12): 919–30.doi:10.1038/nrn1806. PMID 16288298.
10. Wexler NS, Young AB, Tanzi RE, et al. (1987). 'Homozygotes for Huntington's disease'. Nature 326 (6109): 194–197. doi:10.1038/326194a0. PMID 2881213.

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